24 Nov 2016 evidence was collated from ExoCarta, Vesiclepedia and EVpedia. of 8682 protein coding genes collated from ExoCarta, Vesiclepedia and

2017年12月21日 ExoCarta, an exosome database, provides with the contents that were identified in exosomes in multiple organisms. Vesiclepedia -- Database

With In addition, we have initiated an ongoing process of extractions of gene product annotations associated with these terms from Vesiclepedia and ExoCarta, conversion of the extracted annotations to Gene Association File (GAF) format for batch submission to GO, and curation of the submitted annotations by the GO Consortium. Gene product annotations extracted from ExoCarta and Vesiclepedia. At the time of writing this manuscript, 18,695 coding (mRNA and protein) and 963 non-coding (ncRNAs) gene products (including isoforms) were annotated with the GO terms: ‘extracellular vesicle’, ‘extracellular exosome’, ‘apoptotic body’ and ‘microvesicle’ identified in different species (Table 2) from ExoCarta EXOCARTA was the first of these databases to be launch and includes data only from exosomes (http://www.exocarta.org/) [148,149,150,151]. Vesiclepedia was launched later and, now, it gathers information from all classes of extracellular vesicles among them exosomes, microparticles and microvesicles ( http://microvesicles.org/ ) [ 152 , 153 ]. Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment.

Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into the extracellular microenvironment. ectosomes or shedding microvesicles (ii), exosomes and (iii), apoptotic bodies. Recent studies have ignited significant interest on EVs by elucidating their role in intercellular communication, While both Vesiclepedia and EVpedia catalogue data from multiple types of extracellular vesicles, ExoCarta is a primary resource of exosomal cargo and contains annotations on the isolation and characterization methods. The new version of ExoCarta database has more than 2-fold data compared to the last release in 2012 and has new additional features including the annotation of International Society for Extracellular Vesicles (ISEV) standards and dynamic protein–protein interaction networks. Compared to the exosomal database ExoCarta , Vesiclepedia (http://www.microvesicles.org) is a compendium that catalogues proteins, RNAs, lipids and metabolites that are identified in all classes of EVs .

We compared all the proteins identified in our study to those known vesicular proteins in the Exocarta (38, 39) and Vesiclepedia databases (40, 41). Among the 443 identified proteins, 334 (75.4%) proteins were found in previously published data (Figure 3B, Table S2), including the common exosomal markers CD9, CD81, flotillin and syntenin.

ExoCarta, Vesiclepedia, and EVpedia [8–11]. However, consensus regarding the molecular markers to unambiguously distinguish the types of EVs remains to be a problem. Therefore, ‘extracellular vesicle’, which is suggested by the International Society of Extracellular Vesicles (ISEV), is used here for all the secreted vesicles [12].

The currently known data regarding the molecular cargo of extracellular vesicles (lipids, RNAs, and proteins) are summarized in the ExoCarta database [9][10] [11] and in Vesiclepedia, a compendium

These resources aid in elucidating molecular mechanism and pathophysiology underlying different disease conditions from which EVs are isolated. Vesiclepedia: VP_5277: ExoCarta: ExoCarta_5277: Entrez Gene: 5277: HGNC: 8957: MIM: 311770 PIGA identified in extracellular vesicles derived from the following tissue/cell type: Colorectal cancer cells [Microvesicles] More >>> 19930720 : T cells [Microparticles] More >>> 16342139 : Experiment description of studies that identified PIGA in A multitude of EV‐associated miRs have been registered in open‐access databases such as ExoCarta and Vesiclepedia. To date, five studies have reported a total of 39 differentially expressed plasma‐ 5 or serum‐isolated 15 , 29 , 36 , 40 EV‐associated miRs in AD dementia … Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters Citation Kalra, Hina, Richard J. Simpson, Hong Ji, Elena Aikawa, Peter Altevogt, Philip Askenase, Vincent C. Bond, et al. 2012 2018-01-04 Vesiclepedia: VP_9088: ExoCarta: ExoCarta_9088: Entrez Gene: 9088: HGNC: 29650: MIM: 602474 PKMYT1 identified in extracellular vesicles derived from the following tissue/cell type: Colorectal cancer cells [Microvesicles] More >>> 19930720 : Glioblastoma cells [Microvesicles] More >>> 19011622 Table 9: Distribution of Exosomes Isolation Procedures in the Studies Cataloged in ExoCarta Table 10: Statistics of Data Cataloged in ExoCarta, 2012 and 2017 Table 11: Statistics of Data Cataloged in Vesiclepedia, 2012 and 2017 Table 12: Statistics of Data Cataloged in EVpedia, 2018 Table 13: Comparison of Databases for Exosome Studies Exosomes are cell-derived vesicles with the size of 50-150 nm, that are present in many and perhaps all biological fluids, including blood, cerebrospinal fluid, saliva, urine, and cultured medium of cell cultures.Exosomes contain various molecular constituents of their cell of origin, including proteins, DNA and various types of RNA. 2019-05-28 As compared to Vesiclepedia and Exocarta databases, plasma sEVs isolated by the new procedure kept 584 previously identified sEVs-associated proteins and 360 other proteins that have not been detected before. Detailed analysis suggested that more kinds of sEVs biomarkers, such as CD9, ALIX, and FLOT1, John Tanner Wilson.

We also searched abstracts from the annual meetings of the American Association for Cancer Research, and the American Society for Clinical Oncology. Previous version.
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archaea; Gram-positive and Gram-negative bacteria) to complex multicellular ones, suggesting that this extracellular vesicle-mediated communication is evolutionarily conserved. Extracellular. vesicles are spherical bilayered proteolipids with a mean diameter of 20 1,000 nm, which are known to. Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication An overall comparison of EVpedia with Exocarta and Vesiclepedia is shown in Tables I and II. These three web‐based repositories contain proteomic, transcriptomic and lipidomic studies of non‐mammalian eukaryotic and mammalian EVs. However, only EVpedia provides additional proteomic and lipidomic studies on prokaryotic EVs (Table I). Exosomal proteomes derived from CSF, serum and plasma were obtained by accessing three online databases (ExoCarta, Vesiclepedia and EVpedia).

While both Vesiclepedia and EVpedia catalogue data from multiple types of extracellular vesicles, ExoCarta is a primary resource of exosomal cargo [15] and contains annotations on the isolation and characterization methods. Here, we describe Vesiclepedia, a manually curated compendium of molecular data (lipid, RNA and protein) identified in different classes of EVs. Currently, Vesiclepedia comprises 35,264 protein, 18,718 mRNA, 1,772 miRNA and 342 lipid entries encompassed from 341 independent studies that were published over the past several years. ExoCarta (http://www.exocarta.org) is a manually curated database of exosomal proteins, RNA and lipids.
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To benefit the scientific community, existing free Web-based resources including ExoCarta, EVpedia, and Vesiclepedia catalog multiple datasets. These resources aid in elucidating molecular mechanism and pathophysiology underlying different disease conditions from which EVs are isolated.

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has developed and maintains two widely used web-based databases for exosome/extracellular vesicle research, namely ExoCarta and Vesiclepedia.

ExoCarta, an exosome database, provides with the contents that were identified in exosomes in multiple organisms. Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into the extracellular microenvironment. ectosomes or shedding microvesicles (ii), exosomes and (iii), apoptotic bodies. Recent studies have ignited significant interest on EVs by elucidating their role in intercellular communication, While both Vesiclepedia and EVpedia catalogue data from multiple types of extracellular vesicles, ExoCarta is a primary resource of exosomal cargo and contains annotations on the isolation and characterization methods.